The William Shenstone, Moon Under The Water, The Britannia and The Court of Requests will have beers from South Africa, New Zealand, Sweden, Canada, USA, Belgium, Australia, Germany, Spain and Norway.
The Wetherspoons beer festival runs from Friday, March 28 to Sunday, April 13 with all beers priced from £1.99 to £2.15 a pint.
The Moon Under Water manager, Gabrielle Livesey, said: "We are thrilled to be serving such a fantastic selection of beers from across the world as well as those brewed in the UK.
"The overseas beers have never previously been available as cask ales in the UK, which makes them even more special."
Court of Requests manager Anna Haraszkiewicz added: "The festival will be the perfect way for real ale enthusiasts to enjoy a range of excellent beers from overseas brewers.
"It will also give them an opportunity to support brewers throughout the UK, as the pubs are featuring many of their beers."
Many of the beers are available in the pubs for the first time, having been brewed exclusively for the festival.
Customers will be able to sample any three of the real ales in special third of a pint glasses for the price of a pint.