Pavel Pogrebnyak's early goal secured Fulham a 1-0 victory in the west London derby at 10-man QPR.
The Cottagers dominated first-half proceedings in a tense clash with Russia international Pogrebnyak putting the visitors in front.
QPR looked out of sorts for the most part and their task was made harder in the 33rd minute when debutant Samba Diakite was sent off for a second bookable offence - the third home league match out of four a QPR player has received their marching orders in the first period.
After a bright start from the Rs, Fulham found the back of the net in the third minute. Moussa Dembele, playing again in an unusual central midfield role, put through John Arne Riise on the left, and his cross was nodded home off the underside of the bar by Andy Johnson.
The effort was ruled out for offside but the visiting support did not have long to wait to celebrate a goal as Dembele once again proved the catalyst.
The Belgium international's exquisite back heel played through Pogrebnyak, who showed superb composure to round Paddy Kenny and slot home.
The Rs were struggling to get a foothold in the game and their frustrations saw Diakite pick up a booking for a late challenge on Bryan Ruiz in the 20th minute.
The home side's afternoon was made all the more difficult in the 33rd minute when Diakite became the latest Rangers player to earn a first-half red card.
The second period was a much calmer affair as Martin Jol's side welcomed the hosts on, which almost backfired when Jamie Mackie latched on to a Adel Taarabt ball to fire just wide.
Fulham made sweeping changes in a bid to shore things up heading into the final 10 minutes, but were fortunate not to concede in the 83rd minute when Shaun Wright-Phillips somehow curled wide when one-on-one with Mark Schwarzer.